chemotherapy

chemotherapy its a term for the drug treatment of parasitic infections without causing injury to the human. these chemotherapeutic agents can be classified according to several characteristics for example they can classify into:

1. anitbacterial
2. antifungal 
3. antiviral 
4. antiprotozoal 
5. antiheslmentics 

in turn antibacterial agents can be classified by their action into:

1. bacteriostatics; arrest the bacteria growth without killing them; e.g. all sulfonamides  
2. bactericidals; agents that kills bacteria; e.g., aminoglycosides 

note: some agents (drugs) depending on the dose will be bactericidal or bacteriostatics; if present in high dose they are  bactericidal & on low doe they are bacteriostatics

Factors that determine if the drugs is bactericidal or bacterostatics:

1. the mechanism of action of the drug 
2. the dose (refers here to the concentration of the drug at the site of action) 
3. type of microorganism 

also the chemotherapeutic agent could be classified according to the spectrum of activity into:

1. Narrow Spectrum 
2. Extended Spectrum 
3. broad spectrum 

General Principal of chemotherapy:

1. making the diagnosis; as doctor you must know type of infection, the organism & sensitivity testing
2. removal of barrier; making a way for antibiotics to attack the site of infection (if Abscess present then we must open that abscess, drain the buss & clean it very well; so that antibiotics will works very well) 
3. is chemotherapy is a necessary 
4. select the best drugs; refers to "Specificity of the drug" & this done by knowing the pharmacokientics of the drugs; what its the best the drug in case of pregnancy & lactating or if the patient have allergy to certain agents 
5. the cost 
6. optimum dose & frequency